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Put the needle in the same square inch repeatedly and the fat underneath responds the way any tissue does to repeated small trauma: it thickens, it gets lumpy, and the lump absorbs the next dose less predictably than fresh tissue would
The peptide sequence, alanine-histidine-lysine bound to copper, was chosen because of how it interacts with growth factor receptors and anti-apoptotic pathways
growth-hormone-receptor upregulation
This can create a more aged or gaunt look sometimes called Ozempic face. - not a nice phrase in my opinion
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