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Drugs 80 , 11191124 (2020)

Because phentermine activates the sympathetic nervous system, it raises heart rate and blood pressure

along with adrenal fatigue and muscle weakness

249,306,341-343 Several meta-analyses (of predominantly cohort studies) have shown that metabolic bariatric surgery confers significant improvement in cardiovascular risk factors including blood pressure, glycaemia, lipids and waist circumference, compared with medical management