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Hori, M., Nobe, H., Horiguchi, K

Collectively, astrocytic state transitions and the resulting heterogeneity enables glial networks to flexibly sustain neuronal activity and preserve circuit homeostasis

What Does ALCAR Do for Your Brain

Figure 3 elaborates how chemotherapy-sensitive cells undergo DNA damage (crosslinking, DSBs, base modifications) with impaired repair, leading to cell death, whereas resistant cells activate robust DNA repair mechanisms (NHEJ, BER, NER, MMR, HR), effectively repairing damage and promoting survival