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Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo FDA safety, effectiveness, or manufacturing review
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This preserves the natural pulsatile release pattern and negative feedback mechanisms, typically resulting in a safer side effect profile (Prakash & Bhatt, 2013, Indian Journal of Endocrinology and Metabolism )
doi: 10.1038/jcbfm.2015.45 70 GelderblomMLeypoldtFSteinbachKBehrensDChoeCUSilerDAet al
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