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Alternatively, the more supported hypothesis is that there could be hyper-responsivity of the cholinergic receptors at a hypothalamic level, causing a greater decrease in somatostatin tone, and elevated GH release from the anterior pituitary gland (153)

Patients report waking up feeling actually rested, something many of them have not experienced in years

and even as they account for less than 1% of the intestinal epithelium, they establish a complex signaling network, that is likely to be the first step of integration, involving the information obtained from the gut lumen (63, 88, 89)

Methods Lipid peroxidation and antioxidant enzymes activity were estimated using spectrophotometric methods