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Published mechanistic work points to BPC-157 enhancing VEGFR2 expression and downstream signalling activity in endothelial cells, rather than acting as a direct VEGFR2 ligand

It can be concluded that serum GPx activity is low in patients compared to healthy control groups, and the balance between antioxidant and prooxidants is deteriorated in favor of prooxidants, and the deficiency of antioxidant enzymes in diseases may be a symptom in the explanation of cancer pathophysiology