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In a randomized controlled trial, low-dose aspirin improves endothelial cell health in psoriasis via platelet cyclooxygenase-1 (COX-1) inhibition, which reduces the downstream release of membrane-bound arachidonic acid and TxB2(the inactive metabolite of TxA2) (52)
J Agric Food Chem 62:13731383
therefore, we cannot yet conclude whether incomplete MOMP contributes to the modulation of 5FU drug-tolerant persister cells by regulating mitochondrial biogenesis or through independent mechanisms, and we will be explored this possibility in subsequent studies
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