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However, there are several considerations to keep in mind: Sustainability of Weight Loss: While GLP-1 drugs can facilitate weight loss, maintaining this weight loss after discontinuing the medication can be challenging

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We performed comprehensive obesity phenotyping, including measurements of body weight, Lees index, lipid metabolic profiles, and histopathological analysis of adipose tissue

Pratley R, Amod A, Hoff ST, Kadowaki T, Lingvay I, Nauck M, Pedersen KB, Saugstrup T, Meier JJ, PIONEER 4 investigators