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In the event DSIP does ultimately undergo clinical development, intranasal administration can ensure a higher degree of patient compliance by eliminating side effects and discomfort commonly associated with peptide injections
The exercise-MOTS-c connection opens an entirely new avenue of research
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This leads to the accumulation of misfolded or aggregated proteins, the activation of endoplasmic reticulum stress and unfolded protein response, and further aggravation of heat-induced cellular injury (Hetz et al., 2020
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