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Neurology 69 , S14S22 (2007)
In addition to activating PKGI, cGMP itself contributes to smooth muscle relaxation through direct inhibition of the plasma membrane localized L-type Ca 2+ channels
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This epigenetic modification activates GCLC transcription, enhances glutathione synthesis, and protects against lipid peroxidation and ferroptosis, thereby driving chemoresistance in colorectal CSCs
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