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Treatment recommendations may depend on several factors, including: the location of the tear the size of the injury patient age activity level associated ligament injuries the presence of osteoarthritis Some individuals recover successfully with conservative management, while others may require arthroscopic surgery

B12 injections can help correct vitamin B12 deficiency and alleviate associated symptoms, such as fatigue, weakness, and neurological impairments

The absence of published full-text human clinical trials remains the most significant limitation in the evidence base

NEJM 2025 (REDEFINE-2) Novo Nordisk FDA NDA submission announcement (December 18, 2025) Eli Lilly TRIUMPH-4 topline results (December 2025) Frequently Asked Questions Retatrutide produces higher weight loss at 28.7% versus CagriSema's 20.4%a difference of 21 pounds for a 250-pound person