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Patient-level analyses of the SUSTAIN and PIONEER trials found hs-CRP reductions of roughly 24 to 30% versus comparators, and the effect appears only partly explained by weight loss
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Level of Evidence Summary: Diabetic Peripheral Neuropathy: Moderate ([1][6]) Peripheral Neuropathic Pain (General): Moderate[11] Fibromyalgia: Low to Moderate[7][8][9] Central Sensitization/Nociplastic Pain: Low to Moderate (Strong mechanistic rationale
Cytokine 72:8696 Young DS, Pestaner LC, Gibberman V (1975) Effects of drugs on clinical laboratory tests
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