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They did not appear to have an impact on efficacy, as evidenced by comparable changes in VAT and IGF-1 level in patients with or without in vitro neutralizing antibodies

Investigating root causes If two different incretin-based medications have failed, the problem may not be the medications

These can range from mild to serious and may impact your decision to use these medications

In this combined analysis, we observe that the degree of BMI loss depends strongly on sex, drug type, time on treatment and drug dosage, consistent with previous reports 11 , and has a relatively weak dependence on pre-treatment BMI (with higher starting BMI associated with greater BMI loss)