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Like CJC-1295, ipamorelin has no marketing authorisation in the UK
A Phase 2a randomised trial published in Nature Medicine (2024) found that Retatrutide produced an 81.4% (8mg) and 82.4% (12mg) relative reduction in liver fat at 24 weeks, the most significant hepatic fat reduction recorded for a peptide of this class
It contains a combination of two active ingredients: phentermine, an anorectic, and topiramate, an anticonvulsant
Histological and biomechanical recovery were both significantly improved versus controls
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