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It is necessary for the healthy functioning of mitochondria at the cellular level
J Assist Reprod Genet 41:363370
This process has been reported to be significant for tumor development prevention (MacKie et al., 2003
This review examines dysregulation of the KP in MDD, emphasizing KP metabolites particularly quinolinic acid and kynurenic acid as biomarkers and mediators of excitotoxicity, neuroinflammation, and oxidative stress, and discusses the therapeutic efficacy of antidepressants that modulate this pathway
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