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Annual Review of Nutrition , 37 , 371393

After they reached the maximum prescribed dosage (15 milligrams per week), two of the women reported symptoms like a loss of interest in their hobbies or feeling unmotivated to do other healthy things like exercise

In overweight or obese patients without diabetes mellitus, patients treated with GLP-1 RAs had significantly reduced major adverse cardiovascular events, all-cause death, myocardial infarction, and revascularization when compared with placebo [36] [37] [38]