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Identifying appropriate candidates requires evaluating multiple factors including current control, weight status, comorbidities, and treatment goals
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16 For example: Multiple trials in Alzheimer's patients found that GLP-1 receptor agonists did not reduce levels of amyloid beta plaques or tau tangles, nor did they improve cognitive performance, despite showing favorable metabolic effects
Several mechanisms may contribute to the positive effects of GLP1RAs in preventing HF and influencing the outcomes for patients with either HFpEF or HFrEF
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