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Inositol also reduce diabetes health risks including a decreased risk of gestational diabetes in pregnancy by 80% ( Inositol in Obs & Gyne: metabolic syndrome & PCOS 2015 ) A further metanalysis in 2019 found myo-inositol as effective at metformin for improving insulin resistance and reducing androgens

This variability likely reflects differences in study populations, such as the presence or absence of T2DM, degree of obesity, sex distribution, and comorbid conditions, as well as differences in intervention characteristics, including the type, dose, and duration of GLP-1 RA therapy

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