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The 8mg dose produced 21.1% average weight loss, which represents 88% of the maximum doses efficacy with meaningfully better tolerability
In the efficacy-estimand analysis, participants taking the highest dose (12 mg) lost an average of 28.7% of their body weight at 68 weeks, about 71.2 pounds from a baseline of 248.5 pounds
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It is because tissue repair is multifactorial
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