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Low doses of GLP-1 receptor agonists are really powerful for reducing A1C, or the average glucose in the blood, says John Buse, a professor of medicine at UNC School of Medicine and co-director of the North Carolina Translational and Clinical Sciences Institute, in a media release
Together, these findings highlight a metabolic rewiring during neuronal differentiation, characterized by slower accumulation of the labeled intracellular glucose pool in neurons compared to iPSCs, which may underlie the reduced flux into the TCA cycle
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