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A 2015 permeation study confirmed near-zero transdermal delivery through untreated skin (Li et al., 2015)
But the annual cost of these drugs in the US upwards of $11,000 at recent list prices, though net prices may be lower with rebates negotiated by pharmacy benefit managers has raised concerns about the fiscal impact of broad coverage of GLP-1 drugs on Medicare, other health insurers, and patients
Gonzalez-Rellan and Daniel J
This represents a middle ground between brand-name prescriptions and supplements
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