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Iron, copper, zinc, and manganese are cofactors for the antioxidant enzymes catalase and superoxide dismutase, as shown below
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As NAD + is the precursor of NADH, the low levels of both metabolites suggest NAD + depletion while the NAD + /NADH ratio remained unchanged in most of the diseases (Fig
211-214 There is often an inverse relationship between levels of vitamin D and parathyroid hormone, and higher parathyroid levels have also been found to be associated with increased risk for hypertension in adults with obstructive sleep apnea
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