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They use incretin mimetic agents to work on many metabolic paths
The independent and combined hepatic effects of GIP and GLP-1 have been explored in preclinical studies and potential beneficial effects on NAFLD/NASH have been demonstrated [6, 62,63,64,65,66]
The medication may look, smell, and feel normal while delivering significantly reduced efficacy
Supporting this, a recent prospective cohort study has confirmed that significant iron deposition in the caudate nucleus and putamen of patients with T2DM is significantly associated with diminished cognitive performance, manifesting as slower processing speed, declined memory, and poorer executive function, thereby indicating a negative correlation between the degree of iron accumulation in these nuclei and overall cognitive ability (Cheng et al., 2025)
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