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These remain the safest and most sustainable weight-management strategies

Lipscombe L, Butalia S, Dasgupta K, Eurich DT, MacCallum L, Shah BR, et al

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While its indirect effects are highly pronounced in the arterial system, its direct vasoconstrictive action operates predominantly on the venous system, making it highly effective at elevating venous return and central venous pressure (Statler et al, 2023)