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CONTRAINDICATIONS History of hypersensitivity reaction to tirzepatide or any of its excipients Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) PRECAUTIONS Kidney disease No dose adjustment is recommended in patients with any degree of renal impairment Liver disease No dose adjustment is recommended in patients with any degree of liver disease Stomach disorders Tirzepatide slows gastric emptying and is not recommended in patients with significant stomach disorders, including diabetic gastroparesis General anesthesia or deep sedation GLP-1 therapies, like tirzepatide, slow gastric emptying, possibly increasing the risk of residual gastric contents and pulmonary aspiration in patients receiving anesthesia or deep sedation for procedures
Diabetologia 54(4):965978
If the public is going to trust any billionaire with its medications, its probably going to be him
Some of those risks are noteworthy despite GLP-1 RAs good track record in studies, including potential increases in thyroid cancer risk (seen only in animal studies) and the possibility of pancreatitis (seen in human studies).5 6 The decision to offer only testosterone cypionate or testosterone cream as low testosterone treatments when there are other, potentially safer, places for men to start dinged the companys score here a bit.2 In our testing experience, we found it incredibly easy to get a GLP-1 RA prescription
