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A 2024 review surveyed neurotransmitter-system interactions in this body of work (PMID 38675421), suggesting the compound's effects on central nervous system tissue may share mechanisms with its peripheral activity

A person with very high iron levels may experience: weakness fatigue joint pain, often in the hands or knees low sex drive erectile dysfunction (ED) abdominal pain a gray, metallic, or bronze tone to the skin Several health conditions may lead to increased ferritin and iron levels, including: hyperthyroidism hemochromatosis, an inherited disorder alcohol use disorder liver disease porphyria, a group of disorders that affectthe production of heme (a component of hemoglobin) and impact the nervous system or skin certain cancers, including leukemia and Hodgkin lymphoma Other factors that A person with high ferritin levels If a person has low ferritin or iron levels, their doctor will need to evaluate how severe the deficiency is and identify the underlying cause

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