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S., Dias, F
Repeated freeze-thaw cycles cause mechanical stress and can lead to compound aggregation or precipitation out of solution
Dynamic data was first fit into kinetic models with T 1 as an unknown parameter to estimate apparent in vivo T 1 of VitC, which was subsequently incorporated into the kinetic model as a fixed parameter to generate k assuming T 1 is the same across the subjects
Instead, use them at opposite times of day to preserve their activity
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