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New Drug Application (NDA): If clinical trials demonstrate that the drug is safe and effective, the sponsor submits an NDA to the FDA, which includes all data from the trials, labeling information, and manufacturing details

Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by abeta and iron

because of the low incidence of SIS, and based on our findings, it is not possible to rule out either a threefold increase or a decrease in its occurrence among people treated with GLP-1RA

If ERS persists and does not alleviate, UPR will induce apoptosis