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Dosing tiers: Oral administration (500 mcg to 1.5 mg/day) targets gut-specific inflammation: IBD, colitis, and intestinal barrier dysfunction
"IM" means intramuscular injection (into muscle)
Due to its short half-life, it requires frequent dosing to maintain elevated GH levels
This means: No human PK reference data No human bioavailability data No human metabolism or clearance data Rodent-to-human PK extrapolation is therefore speculative This is a major context for research framing
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