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Early data suggests Retatrutide may preserve lean mass slightly better than Tirzepatide, though direct head-to-head comparisons specifically examining body composition in training populations are not available

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Medications like semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and liraglutide (Victoza, Saxenda) slow digestion and curb hunger, which can lead to reduced hunger, a quicker feeling of fullness, or an increased temptation to skip meals

Some want to improve health markers such as blood pressure, cholesterol, or A1C