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Semaglutides effects on alcohol consumption appears larger than other existing FDA-approved medications for alcohol use. Questions remaining This was only a phase II trial with a relatively small sample size, so more data is needed to verify these findings and better understand the potential of GLP-1 therapy as a treatment for substance use disorders
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Consequently, a significant difference of 16S rRNA microbial profiles was noted between low- and high-TMAO producing status ( p = 0.001, R 2 = 0.027) despite a small effect size (Fig
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