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No differences were observed in any of the treatment groups in markers indicative of liver damage (AST and ALT) (Fig
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Exploratory analysis In the semaglutide group, %WL did not significantly differ with age, ethnicity, diabetes status, sex, type of surgery, time from surgery (months), baseline meal-stimulated GLP-1 change, postoperative %WL (from date of surgery (DOS) to randomization), maximum %WL achieved after surgery or MBS response (weight regain versus suboptimal post-surgery weight loss)
For researchers tracking early results on semaglutide and before and after outcomes , the STEP 1 data provides the most rigorous benchmark available
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