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The most frequently reported adverse effects are gastrointestinal in nature and typically occur during treatment initiation or dose escalation
[3] Sermorelin was originally approved in the 1990s for GH deficiency but was later discontinued as a commercial drug for business reasons (not due to safety or efficacy concerns)
PMID 3031680
47,48 These synthetic protein preparations exhibit partial or complete amino acid sequence homology with endogenous GLP-1, rendering them resistant to degradation which resulting in a prolonged half-life and heightened biological activity
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