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The functionality of GLP-1R/CRE Luciferase Reporter HEK293 Cell Line was validated in dose-response assays using the peptide agonists Glucagon-like peptide 1 (7-37), Exendin-4, Lixisenatide, GLP-1 moiety from dulaglutide, Semaglutide, Tirzepatide and Retatrutide
N Engl J Med 2019;381:84151.ArticlePubMed 72
The clinical effects appear to be influenced by several key factors, including patient characteristics (age, gender, ethnicity), concurrent medical conditions (particularly diabetes and obesity), and treatment parameters (drug type, dosage, duration) [9, 10]
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