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The 20.7% figure comes from the STEP-UP trial of 1,742 adults living with obesity, published in NEJM in 2025

Complementary Molecular Mechanisms: Orchestrated Pathway Activation

Hypothyroid animals also have prolonged wound healing due to increased mast cells.[ref][ref][ref] Related article: Thyroid hormones, genetics, and hypothyroidism Asthma and mast cell activation: Mast cells are abundant near the epithelial cells lining the lungs