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Moreover, there have been reports of excessive off-label prescribing and misuse [28,29,30,31,32,33], and the GLP-1 RAs have become popular as a cosmetic weight loss drug by celebrities and are widely promoted on social media [34,35,36,37,38,39]
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If severe hypoglycemia is not treated quickly with a sugar called dextrose, it can result in a coma and even death
Risk increases with: Too few calories or skipped meals , leading to protein breakdown for energy Inadequate protein intake , especially near minimal dietary requirements rather than weight-lossappropriate targets Lack of resistance training , removing the signal to maintain muscle Micronutrient deficiencies , such as low vitamin D, which can impair muscle function Preventing undernutrition dramatically reduces the risk of clinically meaningful muscle loss. How Common Is Lean-Mass Loss with GLP-1/GIP Therapy
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