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Emerging incretin- and multi-agonist-based treatments: the continued refinement and continuous expansion of a potent therapeutic armamentarium for cardio-kidney-liver-metabolic diseases and beyond
The Cost Problem We Cant Ignore I could budget for this medication
[2] Dulaglutide (Trulicity), another once-weekly injectable GLP-1 agonist, demonstrates a somewhat more favourable gastrointestinal tolerability profile in some studies, with nausea reported in approximately 8-12% of patients at lower doses, though rates increase with higher doses (3
The more physiologically relevant studies make use of in vivo transgenic mice, ex vivo perfused intestines or, more recently, crypt organoids derived from human, mouse or porcine guts (55)
