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Glutathione benefits: This molecule acts as the body's master antioxidant, helping to neutralize free radicals, support liver detoxification, and protect cells from oxidative stress

Meet the Experts Dhaval Bhanusali, MD, FAAD, is a board-certified dermatologist, researcher, and laser surgeon based in New York City

2020 [cited 2025 Mar 14]

In this review, we emphasize on (1) GSH depletion as a fundamental risk factor for diseases like chronic obstructive pulmonary disease and atherosclerosis (ischemic heart disease and stroke), (2) importance of oxidative stress and antioxidants in SARS-CoV-2 infection and COVID-19 disease, (3) significance of GSH to counteract persistent damaging inflammation, inflammaging and early (premature) inflammaging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses in younger individuals, and (4) new therapies that include antioxidant defenses restoration