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Weight loss induced by Ozempic may necessitate adjustments to levothyroxine dosing as thyroid hormone requirements change with body composition
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Based on general principles applicable to subcutaneous injectable therapies: Those who do not rotate injection sites adequately , leading to repeated trauma to the same area Individuals on concomitant anticoagulant therapy (for example, warfarin or direct oral anticoagulants), who may experience more pronounced bruising People with a history of allergic skin conditions , who may be more prone to localised irritation, though this has not been specifically studied for retatrutide It should be noted that risk factors relating to specific excipients or the effect of body mass index on injection site reactions cannot be confirmed at this stage, as retatrutide's final formulation details are not yet publicly available in a licensed SmPC
