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In a statement following the EMA PRACs decision, Alison Cave, chief safety officer at the MHRA, said: We are currently reviewing safety data on the risk of suicidal thoughts and thoughts of self-harm associated with medicines known as GLP-1 receptor agonists, used for treating both type 2 diabetes and weight loss

[1] [2] You may notice changes within 1-2 weeks after your last injection, though the full impact may not be apparent for several weeks

Upper/Lower Gastrointestinal Symptoms Adverse event reporting databases, RCTs, and real-world data consistently show that GLP-1 RAs are commonly associated with GI symptoms such as nausea, vomiting, diarrhea, constipation, abdominal pain, and dyspeptic complaints

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