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These reactions mean the body is doing its job and making antibodies

Women with a history of hormone-sensitive conditions , such as oestrogen-receptor-positive breast cancer or endometriosis, should have individualised discussions with their oncologist or specialist before starting semaglutide

GLP-1RAs directly stimulate POMC/CART neurons and indirectly inhibit NPY and AgRP to increase measures of satiety and decrease hunger, resulting in reduced energy intake, thereby facilitating weight loss (Ard et al., 2021) (Figure 6)

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