However, a study that included 97 women with high-frequency episodic migraine or chronic migraine and 146 healthy matched women found, although vitamin D levels were lower in migraine patients, they were not correlated with migraine frequency or with levels of calcitonin gene-related peptide (CGRP), measured on a non-migraine day, suggesting the relationship may not be causal (Haro 2025)
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However, relying on a medication indefinitely can come with trade-offs, like ongoing cost, potential side effects, and dependence on something outside your body to regulate appetite and metabolism
Phytochemistry 116:6977 Coego A, Ramirez V, Gil MJ, Flors V, Mauch-Mani B, Vera P (2005) An Arabidopsis homeodomain transcription factor, overexpressor of cationic peroxidase 3, mediates resistance to infection by necrotrophic pathogens