can you microdose glp-1 Noom GLP-1rx — Low Dose Weight Loss Program Is It Safe to Microdose

Although GLP-1RAs are known to have action in the brain, it is possible one mechanism by which GLP-1RAs reduce consumption of ingested drugs such as alcohol is, at least in part, through peripheral mechanisms

Cardiovasc Diabetol 19:85 Breder I, Cunha Breder J, Bonilha I, Munhoz DB, Medorima STK, Oliveira DC, do Carmo HR, Moreira C, Kontush A, Zimetti F, Zanotti I, Carvalho LSF, Nadruz W, Muscelli E, Quinaglia T, Sposito AC (2020) EXCEED-BHS3 Trial Investigator

PhotoClick cholesterol binding assay PhotoClick cholesterol (37.5 nmoles, 700147P, Avanti Polar Lipids) was agitated in 2 mM MCD in Hanks Balanced Salt Solution (HBSS) (14025092, Thermo Fisher Scientific) overnight at room temperature to facilitate intracellular delivery

Important Safety Note: Both medications carry a boxed warning regarding the risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)