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The median duration on the second GLP-1RA therapy before switching to a third therapy was highest for tirzepatide (5%) at 10.3 months, followed by dulaglutide (32.5%) at 9.4, semaglutide (28%) at 6, liraglutide (32.5%) at 5.6, and exenatide (2%) at 2 months
This treatment has resulted in SVR in 40 80 % of the patients in international datasets (7, 8)
These are real findings, but "increased GLP-1 after a meal" is not the same as "sustained GLP-1 receptor activation at therapeutic levels." Fiber supports gut health and may modestly improve satiety
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