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In EAE, as in human MS, there are selective alterations in TJ proteins, including a notable loss of claudin-3, while other key TJs such as ZO-1, occludin, and claudin-5 are also significantly disrupted, contributing to barrier breakdown and neuroinflammation [135, 136]
Glutathione uses its antioxidant powers to eliminate those toxins and stress, leading to prevention of chronic illness
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