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The lack of efficacy of inhaled GSH in patients with cystic fibrosis could be explained by the high concentrations of the GSH-degrading enzyme -glutamyltransferase present in lung fluids of those patients (116123), and then, the use of precursors of GSH synthesis like NAC and cystine could be more effective in the synthesis of GSH (124)
For these individuals, as well as those living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and dysautonomia, exhaustion is not just feeling tiredit is a profound, cellular depletion of energy
Vitamin C can be found in citrus fruit, and also has antioxidant properties as it can eliminate free radicals from your body and help protect tissues from oxidative stress
Think of these as obstacles that get in the way of glutathione doing its job properly
