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Notably, the insulinotropic and glucagonostatic effects are glucose dependent, and therefore the risk of hypoglycemia is very low during treatment with a GLP-1 RA
Clinical trials have shown promising results for Tirzepatide, with patients losing an average of 11 to 13.1% of their body weight over six months in a phase 2 trial, and even more encouraging results in phase 3 trials
If symptoms interfere with sleep to the extent that you feel chronically fatigued or unable to function normally, medical review is appropriate
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