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This medication may be used off-label for sleep-related eating disorders, nightmares, post-traumatic stress disorder, and alcohol dependence
FOXO1, forkhead box O1
The D-Phe inversion sits inside the conserved His-Phe-Arg-Trp message tetrapeptide that every melanocortin receptor recognises, and it is the substitution responsible for the markedly prolonged receptor occupancy reported for this analogue relative to alpha-MSH, because inverting that stereocentre removes a favoured chymotrypsin-like cleavage point
If results were minimal, redirect resources to approaches with better evidence
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