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In a pre-specified blinded extension for those with a BMI 35, participants who continued on retatrutide 12 mg to 104 weeks lost an average of 85.0 lbs (30.3%)
The entire intestine was removed, rinsed, and chopped into 12 mm pieces in ice-cold Ca 2+ -free Hanks balanced salt solution containing 0.65 mM dithiothreitol, 1% BSA, penicillin, streptomycin, 9.05 mM N a HCO 3 , and 20 mM HEPES
Dosage calculations based on reconstitution concentration and desired dose
These changes can shift numbers within weeks
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