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For example, in certain hereditary kidney diseases, gene editing of iPSCs to introduce pathogenic mutations enables the construction of kidney organoids exhibiting abnormal development and function, facilitating the clarification of genetic mechanisms and improving diagnostic accuracy ( In contrast to hPSC/iPSC-derived kidney organoids used to model developmental and non-neoplastic renal disorders, renal tumor organoids are tissue-derived platforms established directly from patient tumor samples
Methods 14 , 331332 (2017)
BPC-157 research planning splits into two main formats
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